Paxil should be taken once a day, either in the morning or evening, with or without food. Studies have shown Paxil is an excellent treatment for people in this age group - where chronic depression can affect a large proportion of this population. Panic attacks, obsessive compulsive disorders, social anxiety and panic disorders. Panic attacks, obsessive compulsive disorders, social anxiety disorder and generalized anxiety disorder. The therapeutic regimens for those who are suspect of having a depressed state or mood disorder. Do not take Paxil without first talking to your doctor if you experience headache nervousness, or anxiety nausea, diarrhea, or changes in appetite or weight.