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Metformin comes as a tablet and an extended-release tablet to take by mouth. Use this medication regularly in order to get the most benefit from it. Insulin, which promotes the burning of sugar. Most benefit from it. Overall, Metformin reduces blood sugar levels. Glucophage lowers the amount of glucose you absorb from your food and the amount of glucose in the blood. Metformin comes as a tablet and an extended-release tablet to take by mouth. You absorb from your food and the amount of sugar in your blood.