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Corticosteroids produced naturally by the body. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body. Prednisone typically does not produce immediate effects and must be used for several days before the needed effect is achieved. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role. If you are allergic to Prednisolone, or if you have surgery or a medical emergency.