In patients with symptoms of gastro-esophageal reflux disease. Nexium capsules should be applied one hour before meals and at the same time every day. The original Omeprazole product - both prescription drugs used to treat ulcers, gastroesophageal reflux disease, and other conditions caused by excess stomach acid. The majority of gastric ulcers. Esomeprazole reduce the production of acid in the stomach and intestines by blocking the enzyme in the wall of the stomach that produces acid. Nexium is used to treat the infection, which is responsible for the majority of gastric ulcers.