Gabapentin may be effective in some people with bipolar mood disorders that have not responded to lithium. Before Gabapentin is prescribed the patient should have a thorough medical evaluation, including blood and urine tests, to rule out any medical condition that may cause or exacerbate a mood disorder. Gabapentin helps keep the nerve activity in the brain. If people who initially do well on Gabapentin continue to do so after many years of treatment. There are other medications that your doctor may suggest in addition to, pain medications. Patients who have failed to respond to antidepressants or mood stabilizers. Gabapentin may be effective in some people with bipolar mood disorders that have not responded to lithium.