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Celebrex is used to treat arthritis, pain, menstrual cramps, and colonic polyps. Celecoxib is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. It as instructed by your doctor. For the relief of acute pain and the pain of menstrual cramps. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus.