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Nexium is a type of medicine known as an acid pump inhibitor which works by decreasing the acid produced by acid pumps. You will need to take Nexium. Use of Esomeprazole in pregnant women has not been appraised. Nexium is the newer formulation of the original Omeprazole product - both prescription drugs used to treat and prevent stomach and intestinal ulcers, damage to the gastrointestinal tract caused by stomach acid or infection. Along with their useful effects Esomeprazole can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Esomeprazole works best if taken on an empty stomach at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Esomeprazole capsules should be applied one hour before a meal. Nexium is used to treat the infection that causes ulcers occurring just beyond the exit from the stomach.