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The intestines of persons with a family history of this condition. Celecoxib is used for the relief of acute pain and the pain of menstrual cramps. Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine and does not interfere with the function of the blood platelets and, as a result, does not reduce clotting and lead to increased bleeding like other NSAIDs. Celecoxib is used for the relief of acute pain and the pain of menstrual cramps. If you have certain medical conditions.