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If you are taking Valaciclovir for daily therapy, that usually means you take 1 g or alternatively 500 mg once a day, every day. There are no studies that show how well Valaciclovir will work if you take it more than 24 hours after the start of signs or symptoms. You are taking Valaciclovir for daily therapy, that usually means you take 500 mg twice daily for 3 full days.